DISC ONE
Episodes (with Season Play)
- "Dream a Little Dream of Me: Part 1" (43:03)
- "Dream a Little Dream of Me: Part 2" (43:06)
- "Here Comes the Flood" (43:05)
- "Brave New World" (43:04)
"Grey's Anatomy Starter Kit" featurette (4:44)
Start-up Trailers for "abc studios" promo, "The Proposal" and "Blu-ray" promo (4:16)

DISC TWO
Episodes (with Season Play)
- "There's no "I" in Team" (43:02)
- "Life During Wartime" (43:06)
- "Rise Up" (43:03)
- "These Ties That Bind" (43:02)

DISC THREE
Episodes (with Season Play)
- "In the Midnight Hour" (43:07)
- "All By Myself" (43:04)
- "Wish You Were Here" (42:58)
- "Sympathy for the Devil" (43:03)

DISC FOUR
Episodes (with Season Play)
- "Stairway to Heaven" (Extended episode - 49:30)
- "Beat Your Heart Out" (43:03)
- "Before and After" (43:03)
- "An Honest Mistake" (43:04)

DISC FIVE
Episodes (with Season Play)
- "I Will Follow You Into the Dark" (43:04)
- "Stand By Me" (43:01)
- "Elevator Love Letter" (Extended episode - 56:04)
- "Sweet Surrender" (43:05)

DISC SIX
Episodes (with Season Play)
- "No Good at Saying Sorry (One More Chance)" (43:04)
- "What a Difference a Day Makes" (43:04)
- "Here's to Future Days" (43:04)
- "Now Or Never" (43:02)

DISC SEVEN
"100th Episode: Tales From the O.R." featurette (18:32)
"Heaven Sent" featurette (9:29)
"Dissecting Grey's Anatomy: Unaired Scenes" (with Play All - 17:02) (with optional Audio Commentary by creator/executive producer Shonda Rhimes and executive producer Betsy Beers on scenes marked with *)
- "Rise Up"
-- "You Don't Get to Die" (1:26) *
- "These Ties That Bind"
-- "George's Dilemma" (1:42) *
- "Wish You Were Here"
-- "Not Your Friend" (1:12) *
- "Sympathy for the Devil"
-- "Moments" (1:17) *
- "Stairway to Heaven"
-- "So Unexpected" (0:49) *
-- "Help Me or Not?" (0:26)
- "Beat Your Heart Out"
-- "Losing Another Attending" (2:03) *
- "Before and After"
-- "A Simple Guy" (1:19) *
- "Sweet Surrender"
-- "It Can't Just Be Me" (0:51)
- "What a Difference a Day Makes"
-- "Incest Suggestion" (1:00) *
- "Here's to Future Days"
-- "Happy Love Stick" (1:00)
-- "Beach Fantasy" (1:35)
- "Now Or Never"
-- "6 O'clock" (1:35)
-- "Not a Happy Day" (0:39)
"In Stitches: Season Five Outtakes" gag reel (4:06)

Danish, Dutch, English, English HoH, Finnish, Icelandic, Italian, Norwegian, Portuguese, Spanish, Swedish

1.78:1

1080p24 AVC MPEG-4

English DTS-HD Master Audio 5.1
Italian DTS 5.1
Spanish DTS 5.1

Keep Case

Extras are in English with optional Danish, Dutch, Finnish, Icelandic, Italian, Norwegian, Portuguese, Spanish and Swedish subtitles.
"Grey's Anatomy Starter Kit" featurette is in 720i60, rest of the Extras are in 1080p.

DISC ONE
Episodes (with Season Play)
- "Dream a Little Dream of Me: Part 1" (43:03)
- "Dream a Little Dream of Me: Part 2" (43:06)
- "Here Comes the Flood" (43:05)
- "Brave New World" (43:04)
"Grey's Anatomy Starter Kit" featurette (4:44)
Start-up Trailers for "abc studios" promo, "The Proposal" and "Blu-ray" promo (4:16)

DISC TWO
Episodes (with Season Play)
- "There's no "I" in Team" (43:02)
- "Life During Wartime" (43:06)
- "Rise Up" (43:03)
- "These Ties That Bind" (43:02)

DISC THREE
Episodes (with Season Play)
- "In the Midnight Hour" (43:07)
- "All By Myself" (43:04)
- "Wish You Were Here" (42:58)
- "Sympathy for the Devil" (43:03)

DISC FOUR
Episodes (with Season Play)
- "Stairway to Heaven" (Extended episode - 49:30)
- "Beat Your Heart Out" (43:03)
- "Before and After" (43:03)
- "An Honest Mistake" (43:04)

DISC FIVE
Episodes (with Season Play)
- "I Will Follow You Into the Dark" (43:04)
- "Stand By Me" (43:01)
- "Elevator Love Letter" (Extended episode - 56:04)
- "Sweet Surrender" (43:05)

DISC SIX
Episodes (with Season Play)
- "No Good at Saying Sorry (One More Chance)" (43:04)
- "What a Difference a Day Makes" (43:04)
- "Here's to Future Days" (43:04)
- "Now Or Never" (43:02)

DISC SEVEN
"100th Episode: Tales From the O.R." featurette (18:32)
"Heaven Sent" featurette (9:29)
"Dissecting Grey's Anatomy: Unaired Scenes" (with Play All - 17:02) (with optional Audio Commentary by creator/executive producer Shonda Rhimes and executive producer Betsy Beers on scenes marked with *)
- "Rise Up"
-- "You Don't Get to Die" (1:26) *
- "These Ties That Bind"
-- "George's Dilemma" (1:42) *
- "Wish You Were Here"
-- "Not Your Friend" (1:12) *
- "Sympathy for the Devil"
-- "Moments" (1:17) *
- "Stairway to Heaven"
-- "So Unexpected" (0:49) *
-- "Help Me or Not?" (0:26)
- "Beat Your Heart Out"
-- "Losing Another Attending" (2:03) *
- "Before and After"
-- "A Simple Guy" (1:19) *
- "Sweet Surrender"
-- "It Can't Just Be Me" (0:51)
- "What a Difference a Day Makes"
-- "Incest Suggestion" (1:00) *
- "Here's to Future Days"
-- "Happy Love Stick" (1:00)
-- "Beach Fantasy" (1:35)
- "Now Or Never"
-- "6 O'clock" (1:35)
-- "Not a Happy Day" (0:39)
"In Stitches: Season Five Outtakes" gag reel (4:06)

Danish, Dutch, English, English HoH, Finnish, Icelandic, Italian, Norwegian, Portuguese, Spanish, Swedish

1.78:1

1080p24 AVC MPEG-4

English DTS-HD Master Audio 5.1
Italian DTS 5.1
Spanish DTS 5.1

Keep Case

Extras are in English with optional Danish, Dutch, Finnish, Icelandic, Italian, Norwegian, Portuguese, Spanish and Swedish subtitles.
"Grey's Anatomy Starter Kit" featurette is in 720i60, rest of the Extras are in 1080p.
Spanish title: "Anatom�a De Grey".