DISC ONE
Episodes (with Play All)
- "Raindrops Keep Falling on My Head" (43:06)
- "Enough Is Enough (No More Tears)" (43:01)
- "Make Me Lose Control" (43:07)
- "Deny, Deny, Deny" (43:08)
- "Bring the Pain" (43:05)

DISC TWO
Episodes (with Play All)
- "Into You Like a Train" (43:08)
- "Something to Talk About" (43:05)
- "Let It Be" (43:06)
- "Thanks for the Memories" - Extended Episode (48:40)
- "Much Too Much" (43:08)
Audio Commentary on "Into You Like a Train" with director Jeff Melman and Writer Krista Vernoff
Audio Commentary on the Extended Episode "Thanks for the Memories" with creator Shonda Rhimes and editor Susan Vaill

DISC THREE
Episodes (with Play All)
- "Owner of a Lonely Heart" (43:05)
- "Grandma Got Run Over by a Reindeer" (43:02)
- "Begin the Begin" (43:05)
- "Tell Me Sweet Little Lies" (42:42)
- "Break on Through" (43:09)
Audio Commentary on "Grandma Got Run Over by a Reindeer" with actress Sandra Oh and director Peter Horton

DISC FOUR
Episodes (with Play All)
- "It's the End of the World" (Part 1) - Extended Episode (43:11)
- "As We Know It" (Part 2) (43:06)
- "Yesterday" (43:04)
- "What Have I Done to Deserve This?" - Extended Episode (43:20)
- "Band-Aid Covers the Bullet Hole" (43:03)
Audio Commentary on "It's the End of the World" (Part 1) with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Audio Commentary on "As We Know It" (Part 2) with with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas

DISC FIVE
Episodes (with Play All)
- "Superstition" (43:04)
- "The Name of the Game" (43:06)
- "Blues for Sister Someone" (43:07)
- "Damage Case" (42:57)
- "17 Seconds" (43:10)

DISC SIX
Episode
- "Deterioration of the Fight or Flight Response" / "Losing My Religion" - Extended Episode (92:03)
"The Doctors Are In" featurette (13:36)
"The Softer Side of Dr. Bailey" featurette (7:24)
"Creating "Pink Mist"" featurette (5:35)
"A Set Tour Of Seattle Grace Hospital" featurette (7:46)
Dissecting Grey's Anatomy: Unaired Scenes (with Play All) (18:44)
- "Bring the Pain"
-- Reliving the Affair (1:21)
- "Thanks for the Memories"
-- Seattle Might Surprise You (0:41)
- "Tell Me Sweet Little Lies"
-- Want a Dog? (0:12)
- "Break on Through"
-- Lost Shoe (0:52)
-- Place with the Bed (0:38)
- "As We Know It"
-- Chief (1:38)
- "Yesterday"
-- Professional Curiosity (0:17)
-- Apology (0:49)
-- Pudendal Artery (1:17)
- "What Have I Done to Deserve This?"
-- Morning Breath (0:19)
-- Great Catch (1:29)
- "The Name of the Game"
-- Lying or an Idiot (0:48)
-- Knitting (1:01)
- "Blues for Sister Someone"
-- Friends, not Girlfriends (1:00)
- "Damage Case"
-- Got It (0:27)
-- Real Action (0:35)
-- More than a Patient (1:11)
- "Deterioration of the Fight or Flight Response"
-- Finn & Doc (1:10)
- "Losing My Religion"
-- Girl with Cancer (1:13)
-- Things that Matter (1:47)
"Grey's Anatomy on Jimmy Kimmel Live! (with DVD exclusive Jimmy Kimmel Intro)" featurette (22:08)
Start-up Trailers (9:00)
- Apocalypto
- Keeping Up with the Steins
- Scrubs - Season 4
- Pirates of the Caribbean - Dead Man's Chest
- Desperate Housewives - Season 2
Bonus Trailers (with Play All) (15:00)
- Home Improvement - Season 5 (1:28)
- The Golden Girls - Season 6 (1:10)
- Lost - Season 2 (1:26)
- Alias - Season 5 (1:13)
- Grey's Anatomy on ABC (0:32)
- Soap Net (0:31)
- Apocalypto (1:45)
- Keeping Up with the Steins (2:22)
- Scrubs - Season 4 (1:27)
- Pirates of the Caribbean - Dead Man's Chest (2:08)
- Desperate Housewives - Season 2 (0:57)

English HoH

1.78:1

Anamorphic

NTSC

English Dolby Digital 5.1

Digipak

Includes an 8 page booklet.

Special thanks to Rewind user Christian_Bütikofer for providing these specifications.

DISC ONE
Episodes (with Play All)
- "Raindrops Keep Falling on My Head" (43:06)
- "Enough Is Enough (No More Tears)" (43:01)
- "Make Me Lose Control" (43:07)
- "Deny, Deny, Deny" (43:08)
- "Bring the Pain" (43:05)

DISC TWO
Episodes (with Play All)
- "Into You Like a Train" (43:08)
- "Something to Talk About" (43:05)
- "Let It Be" (43:06)
- "Thanks for the Memories" - Extended Episode (48:40)
- "Much Too Much" (43:08)
Audio Commentary on "Into You Like a Train" with director Jeff Melman and Writer Krista Vernoff
Audio Commentary on the Extended Episode "Thanks for the Memories" with creator Shonda Rhimes and editor Susan Vaill

DISC THREE
Episodes (with Play All)
- "Owner of a Lonely Heart" (43:05)
- "Grandma Got Run Over by a Reindeer" (43:02)
- "Begin the Begin" (43:05)
- "Tell Me Sweet Little Lies" (42:42)
- "Break on Through" (43:09)
Audio Commentary on "Grandma Got Run Over by a Reindeer" with actress Sandra Oh and director Peter Horton

DISC FOUR
Episodes (with Play All)
- "It's the End of the World" (Part 1) - Extended Episode (43:11)
- "As We Know It" (Part 2) (43:06)
- "Yesterday" (43:04)
- "What Have I Done to Deserve This?" - Extended Episode (43:20)
- "Band-Aid Covers the Bullet Hole" (43:03)
Audio Commentary on "It's the End of the World" (Part 1) with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Audio Commentary on "As We Know It" (Part 2) with with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas

DISC FIVE
Episodes (with Play All)
- "Superstition" (43:04)
- "The Name of the Game" (43:06)
- "Blues for Sister Someone" (43:07)
- "Damage Case" (42:57)
- "17 Seconds" (43:10)

DISC SIX
Episode
- "Deterioration of the Fight or Flight Response" / "Losing My Religion" - Extended Episode (92:03)
"The Doctors Are In" featurette (13:36)
"The Softer Side of Dr. Bailey" featurette (7:24)
"Creating "Pink Mist"" featurette (5:35)
"A Set Tour Of Seattle Grace Hospital" featurette (7:46)
Dissecting Grey's Anatomy: Unaired Scenes (with Play All) (18:44)
- "Bring the Pain"
-- Reliving the Affair (1:21)
- "Thanks for the Memories"
-- Seattle Might Surprise You (0:41)
- "Tell Me Sweet Little Lies"
-- Want a Dog? (0:12)
- "Break on Through"
-- Lost Shoe (0:52)
-- Place with the Bed (0:38)
- "As We Know It"
-- Chief (1:38)
- "Yesterday"
-- Professional Curiosity (0:17)
-- Apology (0:49)
-- Pudendal Artery (1:17)
- "What Have I Done to Deserve This?"
-- Morning Breath (0:19)
-- Great Catch (1:29)
- "The Name of the Game"
-- Lying or an Idiot (0:48)
-- Knitting (1:01)
- "Blues for Sister Someone"
-- Friends, not Girlfriends (1:00)
- "Damage Case"
-- Got It (0:27)
-- Real Action (0:35)
-- More than a Patient (1:11)
- "Deterioration of the Fight or Flight Response"
-- Finn & Doc (1:10)
- "Losing My Religion"
-- Girl with Cancer (1:13)
-- Things that Matter (1:47)
"Grey's Anatomy on Jimmy Kimmel Live! (with DVD exclusive Jimmy Kimmel Intro)" featurette (22:08)
Start-up Trailers (9:00)
- Apocalypto
- Keeping Up with the Steins
- Scrubs - Season 4
- Pirates of the Caribbean - Dead Man's Chest
- Desperate Housewives - Season 2
Bonus Trailers (with Play All) (15:00)
- Home Improvement - Season 5 (1:28)
- The Golden Girls - Season 6 (1:10)
- Lost - Season 2 (1:26)
- Alias - Season 5 (1:13)
- Grey's Anatomy on ABC (0:32)
- Soap Net (0:31)
- Apocalypto (1:45)
- Keeping Up with the Steins (2:22)
- Scrubs - Season 4 (1:27)
- Pirates of the Caribbean - Dead Man's Chest (2:08)
- Desperate Housewives - Season 2 (0:57)

English HoH

1.78:1

Anamorphic

NTSC

English Dolby Digital 5.1

Digipak

Includes an 8 page booklet.

Special thanks to Rewind user Christian_Bütikofer for providing these specifications.

DISC ONE
Episodes: (with "Play All" option)
- "Raindrops Keep Falling on My Head" (41:24)
- "Enough Is Enough" (41:20)
- "Make Me Lose Control" (41:25)
- "Deny, Deny, Deny" (41:27)
Start-Up Trailers (4:48)
- "Lost" Season 2
- "Alias" Season 5
- "Commander in Chief" Season 1
- "Desperate Housewives" Season 2

DISC TWO
Episodes: (with "Play All" option)
- "Bring the Pain" (41:24)
- "Into You Like a Train" (41:27)
- "Something to Talk About" (41:24)
- "Let It Be" (41:25)
Audio Commentary on "Into You Like a Train" with director Jeff Melman and Writer Krista Vernoff

DISC THREE
Episodes: (with "Play All" option)
- "Thanks for the Memories" (41:23)
- "Much Too Much" (41:27)
- "Owner of a Lonely Heart" (41:24)
- "Grandma Got Run Over by a Reindeer" (41:21)
Audio Commentary on "Thanks for the Memories" with creator Shonda Rhimes and editor Susan Vaill
Audio Commentary on "Grandma Got Run Over by a Reindeer" with actress Sandra Oh and director Peter Horton

DISC FOUR
Episodes: (with "Play All" option)
- "Begin the Begin" (41:23)
- "Tell Me Sweet Little Lies" (41:00)
"A Set Tour of Seattle Grace Hospital" featurette (7:26)
"The Softer Side of Dr. Bailey" featurette (7:09)
"The Doctors Are In" featurette (13:04)
Dissecting Grey's Anatomy: Unaired Scenes (with "Play All" option)
- "Bring the Pain"
-- Reliving the Affair (1:17)
- "Thanks for the Memories"
-- Seattle Might Surprise You (0:36)
-- We Never Had to Schedule Sex (2:11)
-- You Lead, I'll Follow (0:34)
-- They Missed It (0:21)
-- We Did the Right Thing (1:29)
-- What Do You Do? (0:37)
-- Truth Time (0:28)
-- She's Dead Now (0:42)
-- I'm Not Here (0:49)
-- One Day to Be Normal (0:37)
-- He Went Down to the Pit (0:13)
-- Are You Done... Hurting Me? (1:06)
- "Tell Me Sweet Little Lies"
-- Want a Dog? (0:11)

DISC FIVE
Episodes: (with "Play All" option)
- "Break on Through" (41:26)
- "It's the End of the World" (Part 1) (41:21)
- "As We Know It" (Part 2) (41:23)
- "Yesterday" (41:28)
Audio Commentary on "It's the End of the World" (Part 1) with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Audio Commentary on "As We Know It" (Part 2) with with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Start-Up Trailers (4:48)
- "Lost" Season 2
- "Alias" Season 5
- "Commander in Chief" Season 1
- "Desperate Housewives" Season 2

DISC SIX
Episodes: (with "Play All" option)
- "What Have I Done to Deserve This?" (41:23)
- "Band-Aid Covers the Bullet Hole" (41:19)
- "Superstition" (41:21)
- "The Name of the Game" (41:23)

DISC SEVEN
Episodes: (with "Play All" option)
- "Blues for Sister Someone" (41:23)
- "Damage Case" (41:14)
- "17 Seconds" (41:26)
- "Deterioration of the Fight or Flight Response" (41:22)

DISC EIGHT
Episodes: (with "Play All" option)
- "Losing My Religion" (41:18)
"Grey's Anatomy on Jimmy Kimmel Live! (with DVD exclusive Jimmy Kimmel Intro)" featurette (21:15)
"Creating "Pink Mist"" featurette (5:22)
Dissecting Grey's Anatomy: Unaired Scenes
- "Break on Through"
-- Lost Shoe (0:50)
-- Place with the Bed (0:37)
- "It's the End of the World"
-- Was There an Explosion? (0:16)
- "As We Know It"
-- Chief (1:34)
- "Yesterday"
-- Professional Curiosity (0:16)
-- Apology (0:47)
-- Pudendal Artery (1:14)
- "What Have I Done to Deserve This?"
-- Morning Breath (0:18)
-- Great Catch (1:26)
-- What's Wrong? (0:47)
- "The Name of the Game"
-- Lying or an Idiot (0:46)
-- Knitting (0:59)
- "Blues for Sister Someone"
-- Friends, not Girlfriends (0:58)
- "Damage Case"
-- Got It (0:26)
-- Real Action (0:33)
-- More than a Patient (1:08)
- "Deterioration of the Fight or Flight Response"
-- Finn & Doc (1:07)
- "Losing My Religion"
-- Girl with Cancer (1:10)
-- Things That Matter (1:43)
-- And That's How We Raise the Dead (0:25)
-- A Look (0:29)
-- Just One of those Days (1:34)
-- I Could Use a Coma (0:39)
-- Selfish and Neurotic Please (1:41)
-- Woo Hoo Denny (2:01)
-- Color Matters (0:57)
-- Balloons (1:08)
-- He's My Dog (0:36)
-- Thank You for the Prom (1:38)
-- "This is so Unreal" (1:54)
-- When I Got the News (1:02)

English, English HoH, German, and Italian (Optional)

1.78:1

Anamorphic

PAL

English Dolby Digital 5.1
German Dolby Digital 5.1
Italian Dolby Digital 5.1

Keep Case

Menu language. options are in English, German, and Italian.
Trailer audio will be based off selected language options, with some having forced subtitles.
The audio commentaries and extras are in English, with optional German and Italian subtitles.
Packaging is four slim keep cases in a slipcase.

Special thanks to Rewind user Christian_Bütikofer for providing these specifications.

DISC ONE
Episodes: (with "Play All" option)
- "Raindrops Keep Falling on My Head" (41:24)
- "Enough Is Enough" (41:20)
- "Make Me Lose Control" (41:25)
- "Deny, Deny, Deny" (41:27)
Start-Up Trailers (4:48)
- "Lost" Season 2
- "Alias" Season 5
- "Commander in Chief" Season 1
- "Desperate Housewives" Season 2

DISC TWO
Episodes: (with "Play All" option)
- "Bring the Pain" (41:24)
- "Into You Like a Train" (41:27)
- "Something to Talk About" (41:24)
- "Let It Be" (41:25)
Audio Commentary on "Into You Like a Train" with director Jeff Melman and Writer Krista Vernoff

DISC THREE
Episodes: (with "Play All" option)
- "Thanks for the Memories" (41:23)
- "Much Too Much" (41:27)
- "Owner of a Lonely Heart" (41:24)
- "Grandma Got Run Over by a Reindeer" (41:21)
Audio Commentary on "Thanks for the Memories" with creator Shonda Rhimes and editor Susan Vaill
Audio Commentary on "Grandma Got Run Over by a Reindeer" with actress Sandra Oh and director Peter Horton

DISC FOUR
Episodes: (with "Play All" option)
- "Begin the Begin" (41:23)
- "Tell Me Sweet Little Lies" (41:00)
"A Set Tour of Seattle Grace Hospital" featurette (7:26)
"The Softer Side of Dr. Bailey" featurette (7:09)
"The Doctors Are In" featurette (13:04)
Dissecting Grey's Anatomy: Unaired Scenes (with "Play All" option)
- "Bring the Pain"
-- Reliving the Affair (1:17)
- "Thanks for the Memories"
-- Seattle Might Surprise You (0:36)
-- We Never Had to Schedule Sex (2:11)
-- You Lead, I'll Follow (0:34)
-- They Missed It (0:21)
-- We Did the Right Thing (1:29)
-- What Do You Do? (0:37)
-- Truth Time (0:28)
-- She's Dead Now (0:42)
-- I'm Not Here (0:49)
-- One Day to Be Normal (0:37)
-- He Went Down to the Pit (0:13)
-- Are You Done... Hurting Me? (1:06)
- "Tell Me Sweet Little Lies"
-- Want a Dog? (0:11)

DISC FIVE
Episodes: (with "Play All" option)
- "Break on Through" (41:26)
- "It's the End of the World" (Part 1) (41:21)
- "As We Know It" (Part 2) (41:23)
- "Yesterday" (41:28)
Audio Commentary on "It's the End of the World" (Part 1) with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Audio Commentary on "As We Know It" (Part 2) with with show creator Shonda Rhimes, director Peter Horton and editor Edward Ornelas
Start-Up Trailers (4:48)
- "Lost" Season 2
- "Alias" Season 5
- "Commander in Chief" Season 1
- "Desperate Housewives" Season 2

DISC SIX
Episodes: (with "Play All" option)
- "What Have I Done to Deserve This?" (41:23)
- "Band-Aid Covers the Bullet Hole" (41:19)
- "Superstition" (41:21)
- "The Name of the Game" (41:23)

DISC SEVEN
Episodes: (with "Play All" option)
- "Blues for Sister Someone" (41:23)
- "Damage Case" (41:14)
- "17 Seconds" (41:26)
- "Deterioration of the Fight or Flight Response" (41:22)

DISC EIGHT
Episodes: (with "Play All" option)
- "Losing My Religion" (41:18)
"Grey's Anatomy on Jimmy Kimmel Live! (with DVD exclusive Jimmy Kimmel Intro)" featurette (21:15)
"Creating "Pink Mist"" featurette (5:22)
Dissecting Grey's Anatomy: Unaired Scenes
- "Break on Through"
-- Lost Shoe (0:50)
-- Place with the Bed (0:37)
- "It's the End of the World"
-- Was There an Explosion? (0:16)
- "As We Know It"
-- Chief (1:34)
- "Yesterday"
-- Professional Curiosity (0:16)
-- Apology (0:47)
-- Pudendal Artery (1:14)
- "What Have I Done to Deserve This?"
-- Morning Breath (0:18)
-- Great Catch (1:26)
-- What's Wrong? (0:47)
- "The Name of the Game"
-- Lying or an Idiot (0:46)
-- Knitting (0:59)
- "Blues for Sister Someone"
-- Friends, not Girlfriends (0:58)
- "Damage Case"
-- Got It (0:26)
-- Real Action (0:33)
-- More than a Patient (1:08)
- "Deterioration of the Fight or Flight Response"
-- Finn & Doc (1:07)
- "Losing My Religion"
-- Girl with Cancer (1:10)
-- Things That Matter (1:43)
-- And That's How We Raise the Dead (0:25)
-- A Look (0:29)
-- Just One of those Days (1:34)
-- I Could Use a Coma (0:39)
-- Selfish and Neurotic Please (1:41)
-- Woo Hoo Denny (2:01)
-- Color Matters (0:57)
-- Balloons (1:08)
-- He's My Dog (0:36)
-- Thank You for the Prom (1:38)
-- "This is so Unreal" (1:54)
-- When I Got the News (1:02)

English, English HoH, German, and Italian (Optional)

1.78:1

Anamorphic

PAL

English Dolby Digital 5.1
German Dolby Digital 5.1
Italian Dolby Digital 5.1

Keep Case

Menu language. options are in English, German, and Italian.
Trailer audio will be based off selected language options, with some having forced subtitles.
The audio commentaries and extras are in English, with optional German and Italian subtitles.